Hi Sedy! Need button or combination of them (like Ctrl + D) to make box (chest) with drop gone. Ill explain why.
When farming in low lvl map materials like spirit marbles for example ur bag became full fast if u just press E, to make process of farm faster and then around so many boxes where u alr took materials u need and under or close to them new one. And in this moment u have to clean ur bag - delete low items one by one by removing them from bag or wait when this boxes will gone.